Journal: Journal of Advanced Research
Article Title: ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment
doi: 10.1016/j.jare.2024.07.021
Figure Lengend Snippet: Analysis of selected glycogenes in the human uterine endometrium at single-cell resolution across the menstrual cycle. (A) Seven cell clusters from 10x Genomics scRNA-seq dataset ( GSE111976 ) visualized by UMAP projection. (B) Expression patterns of canonical markers ( CDH1 , EPCAM , COL1A1 , COL3A1 , PECAM1 and CD34 ) and (C) eight glycogenes ( FUT2 , FUT4 , FUT8 , ST3GAL1 , ST3GAL6 , ST6GAL1 , ST6GAL2 and ST6GALNAC1 ) of each cell were shown by UMAP plot. (D) Expression patterns of selected eight glycogenes of each cell type were shown by dot plot. Each point in UMAP plots represents a cell (A-C). The color saturation indicates the average expression level (B and C). Each dot in the dot plot represents the expression of the gene in the cell (D), The color saturation indicates the average expression level, and the dot size indicates the percentage of cells expressing the gene (D).
Article Snippet: Analysis of selected glycogenes in the human uterine endometrium at single-cell resolution across the menstrual cycle. (A) Seven cell clusters from 10x Genomics scRNA-seq dataset ( GSE111976 ) visualized by UMAP projection. (B) Expression patterns of canonical markers ( CDH1 , EPCAM , COL1A1 , COL3A1 , PECAM1 and CD34 ) and (C) eight glycogenes ( FUT2 , FUT4 , FUT8 , ST3GAL1 , ST3GAL6 , ST6GAL1 , ST6GAL2 and ST6GALNAC1 ) of each cell were shown by UMAP plot. (D) Expression patterns of selected eight glycogenes of each cell type were shown by dot plot.
Techniques: Expressing